SLC11A1 anticorps (C-Term)

N° du produit ABIN2781545

Détail du produit anti-SLC11A1 anticorps

Antigène: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cobaye, Lapin, Chévre, Cheval, Mouton, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC11A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VLLTRSCAIL PTVLVAVFRD LRDLSGLNDL LNVLQSLLLP FAVLPILTFT

Homologie: Cow: 100%, Dog: 93%, Goat: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against SLC11A1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC11A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 550 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC11A1 (ABIN2781545)

Usuda, Kono, Hayashi, Kawasaki, Mitsui, Shibutani, Dote, Adachi, Fujihara, Shimbo, Sun, Lu, Nakasuji: "Determination of reference concentrations of strontium in urine by inductively coupled plasma atomic emission spectrometry." dans: Environmental health and preventive medicine, Vol. 11, Issue 1, pp. 11-6, (2011) (PubMed).

Détails sur SLC11A1

Antigène: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Autre désignation: SLC11A1 (SLC11A1 Produits)

Synonymes: anticorps SLC11A1, anticorps NRAMP1, anticorps LSH, anticorps NRAMP, anticorps Bcg, anticorps Itg, anticorps Lsh, anticorps Nramp1, anticorps Ity, anticorps Nramp, anticorps ity, anticorps BCG, anticorps solute carrier family 11 member 1 L homeolog, anticorps solute carrier family 11 member 1, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, anticorps slc11a1.L, anticorps SLC11A1, anticorps Slc11a1

Sujet: SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.
Alias Symbols: LSH, NRAMP, NRAMP1
Protein Size: 550

Poids moléculaire: 61 kDa

ID gène: 6556

NCBI Accession: NM_000578, NP_000569

UniProt: P49279

Pathways: Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus