SLC39A4 anticorps (N-Term)

N° du produit ABIN2781713

Détail du produit anti-SLC39A4 anticorps

Antigène: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Épitope: N-Term

Reactivité: Humain, Lapin, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A4 est non-conjugé

Application: Western Blotting (WB)

Séquence: ASLVSLELGL LLAVLVVTAT ASPPAGLLSL LTSGQGALDQ EALGGLLNTL

Homologie: Cow: 86%, Human: 100%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SLC39A4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 647 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC39A4 (ABIN2781713)

Antala, Ovchinnikov, Kamisetty, Baker, Dempski: "Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." dans: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).

Détails sur SLC39A4

Antigène: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Autre désignation: SLC39A4 (SLC39A4 Produits)

Synonymes: anticorps AEZ, anticorps AWMS2, anticorps ZIP4, anticorps 1600025H15Rik, anticorps AU041686, anticorps solute carrier family 39 member 4, anticorps solute carrier family 39 (zinc transporter), member 4, anticorps SLC39A4, anticorps slc39a4, anticorps Slc39a4

Sujet: SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AEZ, FLJ20327, MGC74741, ZIP4, AWMS2
Protein Interaction Partner: UBC,
Protein Size: 647

Poids moléculaire: 68 kDa

ID gène: 55630

NCBI Accession: NM_130849, NP_570901

UniProt: Q6P5W5

Pathways: Transition Metal Ion Homeostasis, Autophagy