SLC5A8 anticorps (Middle Region)

N° du produit ABIN2781721

Détail du produit anti-SLC5A8 anticorps

Antigène: SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC5A8 est non-conjugé

Application: Western Blotting (WB)

Séquence: GILVPFANSI GALVGLMAGF AISLWVGIGA QIYPPLPERT LPLHLDIQGC

Homologie: Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 91%

Attributs du produit: This is a rabbit polyclonal antibody against SLC5A8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC5A8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 610 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC5A8 (ABIN2781721)

Elangovan, Pathania, Ramachandran, Ananth, Padia, Srinivas, Babu, Hawthorn, Schoenlein, Boettger, Smith, Prasad, Ganapathy, Thangaraju: "Molecular mechanism of SLC5A8 inactivation in breast cancer." dans: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3920-35, (2013) (PubMed).

Babu, Ramachandran, CoothanKandaswamy, Elangovan, Prasad, Ganapathy, Thangaraju: "Role of SLC5A8, a plasma membrane transporter and a tumor suppressor, in the antitumor activity of dichloroacetate." dans: Oncogene, Vol. 30, Issue 38, pp. 4026-37, (2011) (PubMed).

Zhang, Bao, Yang, Wu, Yu, Huang, Sun, Zheng, Li: "Activin A induces SLC5A8 expression through the Smad3 signaling pathway in human colon cancer RKO cells." dans: The international journal of biochemistry & cell biology, Vol. 42, Issue 12, pp. 1964-72, (2010) (PubMed).

Détails sur SLC5A8

Antigène: SLC5A8 (Solute Carrier Family 5 (Iodide Transporter), Member 8 (SLC5A8))

Autre désignation: SLC5A8 (SLC5A8 Produits)

Synonymes: anticorps Ait, anticorps SMCT, anticorps SMCT1, anticorps AIT, anticorps RGD1564146, anticorps solute carrier family 5 (iodide transporter), member 8, anticorps solute carrier family 5 member 8, anticorps Slc5a8, anticorps SLC5A8

Sujet: SLC5A8 has been shown to transport iodide by a passive mechanism (Rodriguez et al., 2002 [PubMed 12107270]) and monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism (Gopal et al., 2004 [PubMed 15322102]). In kidney, SLC5A8 functions
Alias Symbols: AIT, MGC125354, SMCT, SMCT1
Protein Size: 610

Poids moléculaire: 66 kDa

ID gène: 160728

NCBI Accession: NM_145913, NP_666018

UniProt: Q8N695