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Osteoactivin anticorps (N-Term)

GPNMB Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Lapin WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2781893
  • Antigène Voir toutes Osteoactivin (GPNMB) Anticorps
    Osteoactivin (GPNMB)
    Épitope
    • 15
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 60
    • 25
    • 24
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Lapin
    Hôte
    • 47
    • 14
    Lapin
    Clonalité
    • 48
    • 13
    Polyclonal
    Conjugué
    • 21
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteoactivin est non-conjugé
    Application
    • 48
    • 22
    • 13
    • 13
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DENDWNEKLY PVWKRGDMRW KNSWKGGRVQ AVLTSDSPAL VGSNITFAVN
    Specificité
    100 % homologous to both isoforms of hGPNMB
    Homologie
    Cow: 100%, Dog: 79%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against GPNMB. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human GPNMB
    Top Product
    Discover our top product GPNMB Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 560 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    Osteoactivin (GPNMB)
    Autre désignation
    GPNMB (GPNMB Produits)
    Synonymes
    anticorps HGFIN, anticorps NMB, anticorps DC-HIL, anticorps Dchil, anticorps ipd, anticorps glycoprotein nmb, anticorps glycoprotein (transmembrane) nmb, anticorps glycoprotein nmb L homeolog, anticorps Gpnmb, anticorps GPNMB, anticorps gpnmb.L
    Sujet
    GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: HGFIN, NMB
    Protein Interaction Partner: UBC, SMAD4, ITSN2,
    Protein Size: 560
    Poids moléculaire
    63 kDa
    ID gène
    10457
    NCBI Accession
    NM_002510, NP_002501
    UniProt
    Q14956
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