CAD anticorps (C-Term)
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- Antigène Voir toutes CAD Anticorps
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Cheval, Cobaye, Boeuf (Vache), Poisson zèbre (Danio rerio), Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CAD est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- ADVVVLRHPQ PGAVELAAKH CRRPVINAGD GVGEHPTQAL LDIFTIREEL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against CAD. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CAD
- Top Product
- Discover our top product CAD Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 2225 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
- Autre désignation
- CAD (CAD Produits)
- Synonymes
- anticorps Cpad, anticorps AU018859, anticorps 2410008J01Rik, anticorps cb456, anticorps wu:fc30c12, anticorps wu:fc33d01, anticorps wu:fc67g02, anticorps si:dkey-221h15.3, anticorps CAD, anticorps xcad, anticorps carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, anticorps CAD, anticorps Cad, anticorps cad
- Sujet
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CAD is a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: -
Protein Interaction Partner: UBC, TUBG1, TP53, SUMO2, SPRTN, STAU1, LGR4, SUMO1, NEDD8, WWOX, NEDD4, FBXO6, HDAC6, ILK, CDK2, HDAC11, HTRA2, TP63, NOS2, ITGA4, RUVBL1, XPO1, VARS, TUBB2A, TUBA4A, SMARCC2, SMARCA4, RPS3, PSMD1, PSMC2, RUVBL2, TUBB4B, SHC1, SMAD2, GRB2, CBL, CUL3, FBXO
Protein Size: 2225 - Poids moléculaire
- 243 kDa
- ID gène
- 790
- NCBI Accession
- NM_004341, NP_004332
- UniProt
- P27708
- Pathways
- Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process
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