ATP6V0A1 anticorps (N-Term)
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- Antigène Voir toutes ATP6V0A1 Anticorps
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
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Épitope
- N-Term
- Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Chien, Poisson zèbre (Danio rerio), Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATP6V0A1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RDLNPDVNVF QRKFVNEVRR CEEMDRKLRF VEKEIRKANI PIMDTGENPE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against ATP6V0A1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A1
- Top Product
- Discover our top product ATP6V0A1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 831 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." dans: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).
: "POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?" dans: Anticancer research, Vol. 28, Issue 2B, pp. 1221-7, (2008) (PubMed).
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ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." dans: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).
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- Antigène
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
- Autre désignation
- ATP6V0A1 (ATP6V0A1 Produits)
- Synonymes
- anticorps ATP6N1, anticorps ATP6N1A, anticorps Stv1, anticorps VPP1, anticorps Vph1, anticorps a1, anticorps AA959968, anticorps ATP6a1, anticorps Atp6n1, anticorps Atp6n1a, anticorps Atpv0a1, anticorps Vpp-1, anticorps Vpp1, anticorps A1, anticorps wu:fj37e01, anticorps zgc:112214, anticorps atp6v0a1, anticorps wu:fc25b09, anticorps zgc:76965, anticorps ATPase H+ transporting V0 subunit a1, anticorps ATPase, H+ transporting, lysosomal V0 subunit A1, anticorps si:ch73-173p19.2, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1 L homeolog, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1b, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1a, anticorps ATP6V0A1, anticorps Atp6v0a1, anticorps si:ch73-173p19.2, anticorps atp6v0a1.L, anticorps atp6v0a1b, anticorps atp6v0a1a
- Sujet
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ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6N1, ATP6N1A, DKFZp781J1951, Stv1, VPP1, Vph1, a1
Protein Interaction Partner: SEH1L, ZNF267, SNX4, UBC, CLIC1, MARCKSL1, MRPL44, SLC30A5, MRPL50, PTRH2, ATP6V1D, MRPL46, SCFD1, VAMP2, SRSF3, RPS18, RPS15, SLC25A3, PA2G4, NONO, ATP6V1E1, ATP6V1B1,
Protein Size: 831 - Poids moléculaire
- 96 kDa
- ID gène
- 535
- NCBI Accession
- NM_005177, NP_005168
- UniProt
- Q93050
- Pathways
- Transition Metal Ion Homeostasis, Proton Transport
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