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ATP6V0A1 anticorps (N-Term)

ATP6V0A1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Chien, Poisson zèbre (Danio rerio), Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2782670
  • Antigène Voir toutes ATP6V0A1 Anticorps
    ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
    Épitope
    • 4
    • 4
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Lapin, Cheval, Chien, Poisson zèbre (Danio rerio), Cobaye
    Hôte
    • 8
    • 1
    Lapin
    Clonalité
    • 9
    Polyclonal
    Conjugué
    • 6
    • 1
    • 1
    • 1
    Cet anticorp ATP6V0A1 est non-conjugé
    Application
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    RDLNPDVNVF QRKFVNEVRR CEEMDRKLRF VEKEIRKANI PIMDTGENPE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against ATP6V0A1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V0A1
    Top Product
    Discover our top product ATP6V0A1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 831 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Leiva-Rodríguez, Romeo-Guitart, Marmolejo-Martínez-Artesero, Herrando-Grabulosa, Bosch, Forés, Casas: "ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons." dans: Cell death & disease, Vol. 9, Issue 6, pp. 626, (2019) (PubMed).

    Antonacopoulou, Grivas, Skarlas, Kalofonos, Scopa, Kalofonos: "POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?" dans: Anticancer research, Vol. 28, Issue 2B, pp. 1221-7, (2008) (PubMed).

  • Antigène
    ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
    Autre désignation
    ATP6V0A1 (ATP6V0A1 Produits)
    Synonymes
    anticorps ATP6N1, anticorps ATP6N1A, anticorps Stv1, anticorps VPP1, anticorps Vph1, anticorps a1, anticorps AA959968, anticorps ATP6a1, anticorps Atp6n1, anticorps Atp6n1a, anticorps Atpv0a1, anticorps Vpp-1, anticorps Vpp1, anticorps A1, anticorps wu:fj37e01, anticorps zgc:112214, anticorps atp6v0a1, anticorps wu:fc25b09, anticorps zgc:76965, anticorps ATPase H+ transporting V0 subunit a1, anticorps ATPase, H+ transporting, lysosomal V0 subunit A1, anticorps si:ch73-173p19.2, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1 L homeolog, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1b, anticorps ATPase, H+ transporting, lysosomal V0 subunit a1a, anticorps ATP6V0A1, anticorps Atp6v0a1, anticorps si:ch73-173p19.2, anticorps atp6v0a1.L, anticorps atp6v0a1b, anticorps atp6v0a1a
    Sujet
    ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ATP6N1, ATP6N1A, DKFZp781J1951, Stv1, VPP1, Vph1, a1
    Protein Interaction Partner: SEH1L, ZNF267, SNX4, UBC, CLIC1, MARCKSL1, MRPL44, SLC30A5, MRPL50, PTRH2, ATP6V1D, MRPL46, SCFD1, VAMP2, SRSF3, RPS18, RPS15, SLC25A3, PA2G4, NONO, ATP6V1E1, ATP6V1B1,
    Protein Size: 831
    Poids moléculaire
    96 kDa
    ID gène
    535
    NCBI Accession
    NM_005177, NP_005168
    UniProt
    Q93050
    Pathways
    Transition Metal Ion Homeostasis, Proton Transport
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