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IL28RA anticorps (N-Term)

IL28RA Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783214
  • Antigène Voir toutes IL28RA Anticorps
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Épitope
    • 16
    • 12
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    N-Term
    Reactivité
    • 42
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye
    Hôte
    • 44
    • 2
    • 1
    Lapin
    Clonalité
    • 46
    • 1
    Polyclonal
    Conjugué
    • 14
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL28RA est non-conjugé
    Application
    • 41
    • 23
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    EECAGTKELL CSMMCLKKQD LYNKFKGRVR TVSPSSKSPW VESEYLDYLF
    Homologie
    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 86%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against IL28RA. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human IL28RA
    Top Product
    Discover our top product IL28RA Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 491 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mucha, Majchrzak, Taciak, Hellmén, Król: "MDSCs mediate angiogenesis and predispose canine mammary tumor cells for metastasis via IL-28/IL-28RA (IFN-?) signaling." dans: PLoS ONE, Vol. 9, Issue 7, pp. e103249, (2014) (PubMed).

  • Antigène
    IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))
    Autre désignation
    IL28RA (IL28RA Produits)
    Synonymes
    anticorps IFNLR1, anticorps IL28RA, anticorps crf2/12, anticorps ifnlr, anticorps il-28r1, anticorps il28ra, anticorps licr2, anticorps ifnlr1, anticorps CRF2-12, anticorps Il28ra, anticorps CRF2/12, anticorps IFNLR, anticorps IL-28R1, anticorps LICR2, anticorps RGD1562689, anticorps interferon lambda receptor 1, anticorps interferon, lambda receptor 1, anticorps interferon, lambda receptor 1 L homeolog, anticorps IFNLR1, anticorps ifnlr1, anticorps ifnlr1.L, anticorps Ifnlr1
    Sujet
    IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Alias Symbols: CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA
    Protein Interaction Partner: IFNLR1, IFNL1, IFNL2, LSM8,
    Protein Size: 491
    Poids moléculaire
    54 kDa
    ID gène
    163702
    NCBI Accession
    NM_173064, NP_775087
    UniProt
    Q5VTX8
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