ATP5B anticorps (N-Term)

N° du produit ABIN2783268

Détail du produit anti-ATP5B anticorps

Antigène: ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Porc, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP5B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 529 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ATP5B (ABIN2783268)

Li, Bates, An, Terry, Wang: "Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." dans: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).

Zischka, Lichtmannegger, Schmitt, Jägemann, Schulz, Wartini, Jennen, Rust, Larochette, Galluzzi, Chajes, Bandow, Gilles, DiSpirito, Esposito, Goettlicher, Summer, Kroemer: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." dans: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).

Guo, Prokai-Tatrai, Nguyen, Rauniyar, Ughy, Prokai: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." dans: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).

Détails sur ATP5B

Antigène: ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))

Autre désignation: ATP5B (ATP5B Produits)

Synonymes: anticorps atpmb, anticorps atpsb, anticorps Atpsyn-beta, anticorps hm:zehn0534, anticorps im:6793121, anticorps wu:fj38d01, anticorps zgc:111961, anticorps ATPMB, anticorps ATPSB, anticorps ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide, anticorps ATP synthase subunit beta, mitochondrial, anticorps ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit, anticorps ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide S homeolog, anticorps ATP5B, anticorps atp5b, anticorps Atp5b, anticorps LOC100401662, anticorps LOC100635763, anticorps atp5b.S

Sujet: ATP5B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5B is the beta subunit of the catalytic core.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATPMB, ATPSB, MGC5231
Protein Interaction Partner: FUS, FDX1, ATP5A1, HUWE1, ATPAF2, TRIM63, TRIM55, SPRTN, STAU1, GRSF1, UBC, MDM2, ASB5, ASB11, SUZ12, RNF2, EZH2, BMI1, GBP1, ADRB2, TERT, vpu, UBL4A, WHSC1, VCAM1, PPP1CC, ITGA4, FN1, ESR1, ATF2, BTK, YWHAE, SUMO2, CA9, FMNL1, ATP5O, ATP6V1B2, ATP5C1, AT
Protein Size: 529

Poids moléculaire: 52 kDa

ID gène: 506

NCBI Accession: NM_001686, NP_001677

UniProt: P06576

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process