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NUDT15 anticorps (N-Term)

NUDT15 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval, Saccharomyces cerevisiae WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2783521
  • Antigène Voir toutes NUDT15 Anticorps
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    Épitope
    • 15
    • 8
    • 6
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin, Poisson zèbre (Danio rerio), Cheval, Saccharomyces cerevisiae
    Hôte
    • 24
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp NUDT15 est non-conjugé
    Application
    • 19
    • 16
    • 16
    • 14
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    RKGSFGAGSF QLPGGHLEFG ETWEECAQRE TWEEAGLHLK NVCFASVVNS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 79%
    Attributs du produit
    This is a rabbit polyclonal antibody against Nudt15. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product NUDT15 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 170 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
    Autre désignation
    Nudt15 (NUDT15 Produits)
    Synonymes
    anticorps MTH2, anticorps RP11-90M2.1, anticorps 6530403O17, anticorps A730068G11Rik, anticorps nudix hydrolase 15, anticorps nudix (nucleoside diphosphate linked moiety X)-type motif 15, anticorps NUDT15, anticorps Nudt15
    Sujet
    Nudt15 mediates the hydrolysis of some nucleoside diphosphate derivatives. It can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. Nudt15 may have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
    Alias Symbols: 6530403O17, A730068G11Rik, MTH2
    Protein Size: 170
    Poids moléculaire
    19 kDa
    ID gène
    214254
    NCBI Accession
    NM_172527, NP_766115
    UniProt
    Q8BG93
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