LMBR1 anticorps (N-Term)

N° du produit ABIN2783870

Détail du produit anti-LMBR1 anticorps

Antigène: LMBR1 (Limb Region 1 Homolog (LMBR1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMBR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: MEGQDEVSAR EQHFHSQVRE STICFLLFAI LYVVSYFIIT RYKRKSDEQE

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against LMBR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human LMBR1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 490 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur LMBR1

Antigène: LMBR1 (Limb Region 1 Homolog (LMBR1))

Autre désignation: LMBR1 (LMBR1 Produits)

Synonymes: anticorps im:7156444, anticorps LMBR1, anticorps ACHP, anticorps C7orf2, anticorps DIF14, anticorps PPD2, anticorps TPT, anticorps ZRS, anticorps RGD1563910, anticorps 1110048D14Rik, anticorps AU017641, anticorps limb region 1 homolog (mouse), anticorps limb development membrane protein 1, anticorps limb region 1, anticorps lmbr1, anticorps LMBR1, anticorps Lmbr1

Sujet: LMBR1 is a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of LMBR1 gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if LMBR1 gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACHP, C7orf2, DIF14, FLJ11665, PPD2, TPT
Protein Interaction Partner: UBC,
Protein Size: 490

Poids moléculaire: 55 kDa

ID gène: 64327

NCBI Accession: NM_022458, NP_071903

UniProt: Q8WVP7