CYP2R1 anticorps (Middle Region)

N° du produit ABIN2783924

Détail du produit anti-CYP2R1 anticorps

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Épitope: Middle Region

Reactivité: Humain, Souris, Chien, Cheval, Porc, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2R1 est non-conjugé

Application: Western Blotting (WB)

Séquence: FKQLITNAVS NITNLIIFGE RFTYEDTDFQ HMIELFSENV ELAASASVFL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against CYP2R1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human CYP2R1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 501 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP2R1

Antigène: CYP2R1 (Cytochrome P450, Family 2, Subfamily R, Polypeptide 1 (CYP2R1))

Autre désignation: CYP2R1 (CYP2R1 Produits)

Synonymes: anticorps cytochrome P450 family 2 subfamily R member 1, anticorps cytochrome P450, family 2, subfamily R, polypeptide 1, anticorps cytochrome P450, family 2, subfamily r, polypeptide 1, anticorps CYP2R1, anticorps cyp2r1, anticorps Cyp2r1

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Alias Symbols: MGC4663
Protein Size: 501

Poids moléculaire: 57 kDa

ID gène: 120227

NCBI Accession: NM_024514, NP_078790

UniProt: Q6VVX0

Pathways: Metabolism of Steroid Hormones and Vitamin D