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SPRY2 anticorps (N-Term)

SPRY2 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Porc, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2784217
  • Antigène Voir toutes SPRY2 Anticorps
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    Épitope
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 37
    • 18
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Porc, Cobaye
    Hôte
    • 37
    • 3
    • 1
    • 1
    Lapin
    Clonalité
    • 39
    • 3
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp SPRY2 est non-conjugé
    Application
    • 34
    • 25
    • 11
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    MEARAQSGNG SQPLLQTPRD GGRQRGEPDP RDALTQQVHV LSLDQIRAIR
    Homologie
    Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SPRY2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SPRY2
    Top Product
    Discover our top product SPRY2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 315 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Hsu, Lee, Hartstein, Harocopos: "Clostridium perfringens Keratitis Leading to Blinding Panophthalmitis." dans: Cornea, Vol. 27, Issue 10, pp. 1200-3, (2008) (PubMed).

  • Antigène
    SPRY2 (Sprouty Homolog 2 (SPRY2))
    Autre désignation
    SPRY2 (SPRY2 Produits)
    Synonymes
    anticorps wu:fk66h11, anticorps wu:fk93e11, anticorps zgc:110440, anticorps hspry2, anticorps xspry2, anticorps sprouty2, anticorps Xsprouty2, anticorps sprouty-2, anticorps Xtsprouty2, anticorps hSPRY2, anticorps sprouty RTK signaling antagonist 2, anticorps sprouty RTK signaling antagonist 2 S homeolog, anticorps sprouty homolog 2 (Drosophila), anticorps spry2, anticorps SPRY2, anticorps spry2.S, anticorps Spry2
    Sujet
    SPRY2 is a protein belonging to the sprouty family. It contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. SPRY2 is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. SPRY2 may play a role in alveoli branching during lung development as shown by a similar mouse protein.This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MGC23039, hSPRY2
    Protein Interaction Partner: PTGER3, PRKAB2, KRTAP4-11, ATRIP, KRTAP5-6, KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, LCE3E, KRTAP5-9, GP9, OTX1, MLLT6, MEOX2, MDFI, LASP1, LCE2D, LCE1B, RUNX1T1, AQP1, LCE3C, LCE4A, ZNF417, HEXIM2, CATSPER1, LONRF1, KRTAP4-7, KR
    Protein Size: 315
    Poids moléculaire
    35 kDa
    ID gène
    10253
    NCBI Accession
    NM_005842, NP_005833
    UniProt
    O43597
    Pathways
    EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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