NR4A3 anticorps (Middle Region)

N° du produit ABIN2784460

Détail du produit anti-NR4A3 anticorps

Antigène: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cheval, Chien, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR4A3 est non-conjugé

Application: Western Blotting (WB)

Séquence: VKVSDFGMAR YVLDDQYTSS SGAKFPVKWC PPEVFNYSRF SSKSDVWSFG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against TEC. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TEC

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 631 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NR4A3

Antigène: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Autre désignation: TEC (NR4A3 Produits)

Synonymes: anticorps CHN, anticorps CSMF, anticorps MINOR, anticorps NOR1, anticorps TEC, anticorps AI573420, anticorps NOR-1, anticorps Nor1, anticorps NOR-2, anticorps NR4A3, anticorps Nr4a3, anticorps nuclear receptor subfamily 4 group A member 3, anticorps nuclear receptor subfamily 4, group A, member 3, anticorps NR4A3, anticorps Nr4a3, anticorps nr4a3

Sujet: The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.
Alias Symbols: MGC126760, MGC126762, PSCTK4
Protein Interaction Partner: ERBB2, MED28, GRB2, SHC1, FASLG, Nedd4, UBC, IKBKG, STAP1, PIP4K2A, PLK4, PTPN18, PIK3R3, GNA12, SOCS1, PIP5K1A, PTPN21, DOK1, TEC, PLCG2, WAS, BTK, BMX, TP53, PRLR, PLCG1, PIK3R1, LYN, KIT, VAV1, JAK2, JAK1, ARHGEF12, GNA13, RHOA, RAC1, PIK3R2,
Protein Size: 631

Poids moléculaire: 73 kDa

ID gène: 7006

NCBI Accession: NM_003215, NP_003206

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway