DYNLL1 anticorps (N-Term)
-
- Antigène Voir toutes DYNLL1 Anticorps
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat, Cheval, Lapin, Cobaye, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp DYNLL1 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- MCDRKAVIKN ADMSEEMQQD SVECATQALE KYNIEKDIAA HIKKEFDKKY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against DYNLL1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human DYNLL1
- Top Product
- Discover our top product DYNLL1 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 89 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- DYNLL1 (Dynein, Light Chain, LC8-Type 1 (DYNLL1))
- Autre désignation
- DYNLL1 (DYNLL1 Produits)
- Synonymes
- anticorps DLC1, anticorps DLC8, anticorps DNCL1, anticorps DNCLC1, anticorps LC8, anticorps LC8a, anticorps PIN, anticorps hdlc1, anticorps dynll2, anticorps wu:fd56c09, anticorps zgc:73406, anticorps Dlc8, anticorps Dnclc1, anticorps Pin, anticorps 8kDLC, anticorps lc8, anticorps dlc1, anticorps dlc8, anticorps lc8a, anticorps dncl1, anticorps dnclc1, anticorps dynll1a, anticorps MGC68763, anticorps CDLC2, anticorps dynll1, anticorps dynll1b, anticorps pin, anticorps MGC89636, anticorps dynein light chain LC8-type 1, anticorps dynein, light chain, LC8-type 1, anticorps dynein light chain LC8-type 1 S homeolog, anticorps dynein light chain LC8-type 1 L homeolog, anticorps Dynein light chain 1, cytoplasmic, anticorps DYNLL1, anticorps dynll1, anticorps Dynll1, anticorps dynll1.S, anticorps dynll1.L, anticorps dlc-1
- Sujet
-
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.
Alias Symbols: DLC1, DLC8, DNCL1, DNCLC1, LC8, LC8a, MGC126137, MGC126138, PIN, hdlc1
Protein Interaction Partner: UBC, DYNC1I1, CCDC36, IQUB, AMBRA1, AMOTL2, KANK2, BECN1, BMI1, EED, GNB2L1, RPS21, RPS5, RPS3, RPS2, RPSA, HDLBP, FKBP3, FAU, DYNC1LI2, NRF1, AMOT, DYRK1B, DYRK1A, TERT, STK24, PRKACB, PRKACA, GSK3B, STK26, STK25, CSNK1A1, PAK1, UL122, IQCB1, BCL2L11, NA
Protein Size: 89 - Poids moléculaire
- 10 kDa
- ID gène
- 8655
- NCBI Accession
- NM_001037494, NP_001032583
- UniProt
- P63167
- Pathways
- M Phase, Tube Formation, Positive Regulation of Endopeptidase Activity
-