PACS2 anticorps (Middle Region)

N° du produit ABIN2784562

Détail du produit anti-PACS2 anticorps

Antigène: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PACS2 est non-conjugé

Application: Western Blotting (WB)

Séquence: AHQLPIAEAM LTYKQKSPDE ESSQKFIPFV GVVKVGIVEP SSATSGDSDD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PACS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PACS2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 889 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PACS2

Antigène: PACS2 (phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))

Autre désignation: PACS2 (PACS2 Produits)

Synonymes: anticorps PACS-2, anticorps PACS1L, anticorps 6720425G15Rik, anticorps AW208651, anticorps AW489976, anticorps E230011J22, anticorps Pacs1l, anticorps mKIAA0602, anticorps phosphofurin acidic cluster sorting protein 2, anticorps PACS2, anticorps Pacs2

Sujet: PACS2 is the multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer,PACS2 translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death.PACS2 may also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Alias Symbols: FLJ25488, KIAA0602, PACS1L, PACS-2
Protein Interaction Partner: UBC, TRAF2, BIRC3, BIRC2, PKD2, BID,
Protein Size: 889

Poids moléculaire: 98 kDa

ID gène: 23241

NCBI Accession: NM_015197, NP_056012

UniProt: Q86VP3