ACVR1C/ALK7 anticorps (N-Term)

N° du produit ABIN2785115

Détail du produit anti-ACVR1C/ALK7 anticorps

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR1C/ALK7 est non-conjugé

Application: Western Blotting (WB)

Séquence: QVFCHSSNNV TKTECCFTDF CNNITLHLPT ASPNAPKLGP MELAIIITVP

Homologie: Cow: 100%, Dog: 83%, Guinea Pig: 80%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 81%, Rabbit: 100%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ACVR1C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ACVR1C

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 493 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ACVR1C/ALK7

Antigène: ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))

Autre désignation: ACVR1C (ACVR1C Produits)

Synonymes: anticorps ACVRLK7, anticorps ALK7, anticorps Alk-7, anticorps C230097P10, anticorps Alk7, anticorps habrec1, anticorps activin A receptor type 1C, anticorps activin A receptor, type IC, anticorps ACVR1C, anticorps Acvr1c

Sujet: ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM].
Alias Symbols: ACVRLK7, ALK7
Protein Interaction Partner: HSP90AA1, TDGF1, INHBB,
Protein Size: 493

Poids moléculaire: 55 kDa

ID gène: 130399

NCBI Accession: NM_145259, NP_660302

UniProt: Q8NER5

Pathways: Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity