APH1B anticorps (N-Term)

N° du produit ABIN2785589

Détail du produit anti-APH1B anticorps

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Épitope: N-Term

Reactivité: Souris, Humain, Rat, Lapin, Boeuf (Vache), Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1B est non-conjugé

Application: Western Blotting (WB)

Séquence: IIDNKDGPTQ KYLLIFGAFV SVYIQEMFRF AYYKLLKKAS EGLKSINPGE

Homologie: Cow: 92%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human APH1B

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur APH1B

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Autre désignation: APH1B (Aph1b Produits)

Synonymes: anticorps APH-1B, anticorps PRO1328, anticorps PSFL, anticorps TAAV688, anticorps APH-1B', anticorps 2310057K14Rik, anticorps Aph1c, anticorps aph-1 homolog B, gamma-secretase subunit, anticorps aph-1 homolog B, gamma secretase subunit, anticorps aph1 homolog B, gamma secretase subunit, anticorps APH1B, anticorps Aph1b

Sujet: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.
Alias Symbols: APH-1B, PRO1328, PSFL, TAAV688
Protein Interaction Partner: UBC, PSENEN, NCSTN, PSEN2, PSEN1,
Protein Size: 257

Poids moléculaire: 28 kDa

ID gène: 83464

NCBI Accession: NM_031301, NP_112591

UniProt: Q8WW43

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway