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GLE1 anticorps (N-Term)

GLE1 Reactivité: Humain, Rat, Souris, Cheval, Porc, Lapin, Boeuf (Vache), Saccharomyces cerevisiae, Chien, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2785781
  • Antigène Voir toutes GLE1 Anticorps
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Épitope
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Rat, Souris, Cheval, Porc, Lapin, Boeuf (Vache), Saccharomyces cerevisiae, Chien, Poisson zèbre (Danio rerio)
    Hôte
    • 13
    • 3
    Lapin
    Clonalité
    • 15
    • 1
    Polyclonal
    Conjugué
    • 12
    • 2
    • 1
    • 1
    Cet anticorp GLE1 est non-conjugé
    Application
    • 11
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    LKLREAEQQR VKQAEQERLR KEEGQIRLRA LYALQEEMLQ LSQQLDASEQ
    Homologie
    Cow: 93%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 100%, Yeast: 90%, Zebrafish: 77%
    Attributs du produit
    This is a rabbit polyclonal antibody against GLE1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human GLE1
    Top Product
    Discover our top product GLE1 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 659 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    GLE1 (GLE1 RNA Export Mediator (GLE1))
    Autre désignation
    GLE1 (GLE1 Produits)
    Synonymes
    anticorps Dmel\\CG14749, anticorps GLE1, anticorps GLE1L, anticorps LCCS, anticorps LCCS1, anticorps hGLE1, anticorps Gle1l, anticorps 4933405K21Rik, anticorps AA553313, anticorps CG14749 gene product from transcript CG14749-RA, anticorps nucleoporin GLE1, anticorps RNA export factor Gle1, anticorps GLE1, RNA export mediator, anticorps GLE1 RNA export mediator, anticorps GLE1 RNA export mediator (yeast), anticorps CG14749, anticorps CpipJ_CPIJ014147, anticorps SJAG_03847, anticorps GLE1, anticorps Gle1
    Sujet
    GLE1 is a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm.This gene encodes a predicted 75- kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: GLE1L, hGLE1, LCCS, LCCS1
    Protein Interaction Partner: RNF2, UBC, ELAVL1, NUPL2, NUP155, EIF3F, UXT, KRT10,
    Protein Size: 659
    Poids moléculaire
    75 kDa
    ID gène
    2733
    NCBI Accession
    NM_001499, NP_001490
    UniProt
    Q53GS7
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