PAD4 anticorps (Middle Region)

N° du produit ABIN2785937

Détail du produit anti-PAD4 anticorps

Antigène: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Lapin, Mouton, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cobaye, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAD4 est non-conjugé

Application: Western Blotting (WB)

Séquence: TGGISGLDSF GNLEVSPPVT VRGKEYPLGR ILFGDSCYPS NDSRQMHQAL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 87%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 86%, Rat: 100%, Sheep: 79%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against PADI4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PADI4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 663 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PAD4 (ABIN2785937)

Costenbader, Chang, De Vivo, Plenge, Karlson: "Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking." dans: Arthritis research & therapy, Vol. 10, Issue 3, pp. R52, (2008) (PubMed).

Détails sur PAD4

Antigène: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Autre désignation: PADI4 (PADI4 Produits)

Synonymes: anticorps PAD, anticorps PAD4, anticorps PADI5, anticorps PDI4, anticorps PDI5, anticorps Pad4, anticorps Pdi4, anticorps peptidyl arginine deiminase 4, anticorps peptidyl arginine deiminase, type IV, anticorps PADI4, anticorps Padi4

Sujet: PADI4 is an enzyme responsible for the conversion of arginine residues to citrulline residues. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response.This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAD, PADI5, PDI4, PDI5, PAD4
Protein Interaction Partner: ANXA4, FBXO25, APP, ING4, ELK1, NPM1, TP53, HDAC2, HIST2H3A, HDAC1, TFF1, HIST4H4, HIST3H3,
Protein Size: 663

Poids moléculaire: 74 kDa

ID gène: 23569

NCBI Accession: NM_012387, NP_036519

UniProt: Q9UM07