AGTPBP1 anticorps (C-Term)

N° du produit ABIN2786096

Détail du produit anti-AGTPBP1 anticorps

Antigène: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGTPBP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: GMQPLMYSVQ EALNARPWWI RMGTDICYYK NHFSRSSVAA GGQKGKSYYT

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against Agtpbp1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Agtpbp1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1160 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur AGTPBP1

Antigène: AGTPBP1 (ATP/GTP Binding Protein 1 (AGTPBP1))

Autre désignation: Agtpbp1 (AGTPBP1 Produits)

Synonymes: anticorps ccp1, anticorps AGTPBP1, anticorps CCP1, anticorps NNA1, anticorps 1700020N17Rik, anticorps 2310001G17Rik, anticorps 2900054O13Rik, anticorps 4930445M19Rik, anticorps 5730402G09Rik, anticorps BB114605, anticorps Nna1, anticorps mKIAA1035, anticorps nmf243, anticorps pcd, anticorps si:ch73-236b16.2, anticorps ATP/GTP binding protein 1 L homeolog, anticorps ATP/GTP binding protein 1, anticorps agtpbp1.L, anticorps AGTPBP1, anticorps agtpbp1, anticorps Agtpbp1

Sujet: Agtpbp1 is a metallocarboxypeptidase that mediates deglutamylation of target proteins. It catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. It also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Agtpbp1 acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell differentiation, accumulation of tubulin polyglutamylation causing neurodegeneration.
Alias Symbols: 1700020N17Rik, 2310001G17Rik, 2900054O13Rik, 4930445M19Rik, 5730402G09Rik, BB114605, CCP1, Nna1, mKIAA1035, nmf243, pcd
Protein Size: 1160

Poids moléculaire: 128 kDa

ID gène: 67269

NCBI Accession: NM_023328, NP_075817

Pathways: Proton Transport