APBB2 anticorps (Middle Region)

N° du produit ABIN2786292

Détail du produit anti-APBB2 anticorps

Antigène: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Lapin, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APBB2 est non-conjugé

Application: Western Blotting (WB)

Séquence: QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against APBB2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human APBB2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 736 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-APBB2 (ABIN2786292)

Hong, Hsu, Schultz, Pratt, Mattison, Chang: "Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response." dans: BMC molecular biology, Vol. 8, pp. 50, (2007) (PubMed).

Détails sur APBB2

Antigène: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Autre désignation: APBB2 (APBB2 Produits)

Synonymes: anticorps FE65L, anticorps FE65L1, anticorps 2310007D03Rik, anticorps Rirl1, anticorps TR2L, anticorps Zfra, anticorps RGD1562438, anticorps APBB2, anticorps fe65l, anticorps fe65l1, anticorps DKFZp469I236, anticorps si:ch211-201g8.2, anticorps amyloid beta precursor protein binding family B member 2, anticorps amyloid beta (A4) precursor protein-binding, family B, member 2, anticorps amyloid beta (A4) precursor protein-binding, family B, member 2b, anticorps APBB2, anticorps Apbb2, anticorps apbb2, anticorps apbb2b

Sujet: APBB2 may modulate the internalization of beta-amyloid precursor protein.The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.
Alias Symbols: FE65L, FE65L1, MGC35575
Protein Interaction Partner: UBC, EGFR, SMURF1, SMAD4, APLP2, APP,
Protein Size: 736

Poids moléculaire: 81 kDa

ID gène: 323

NCBI Accession: NM_173075, NP_775098

UniProt: Q92870