PRKACB anticorps (Middle Region)

N° du produit ABIN2786691

Détail du produit anti-PRKACB anticorps

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Cobaye, Cheval, Lapin, Chien, Mouton, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKACB est non-conjugé

Application: Western Blotting (WB)

Séquence: NGVSDIKTHK WFATTDWIAI YQRKVEAPFI PKFRGSGDTS NFDDYEEEDI

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 92%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against PRKACB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PRKACB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 351 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRKACB

Antigène: PRKACB (Protein Kinase, CAMP Dependent, Catalytic, beta (PRKACB))

Autre désignation: PRKACB (PRKACB Produits)

Sujet: CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.
Alias Symbols: DKFZp781I2452, MGC41879, MGC9320, PKACB
Protein Interaction Partner: APPBP2, UBC, TP53RK, TPRKB, KIAA1279, ARPC2, ACTR2, ACTR3, ARPC1B, ARPC4, SUMO1, PFDN1, CDK5RAP2, MAPRE1, AKAP11, DCAF7, AKAP9, TRAP1, PDE4DIP, AKAP5, AKAP7, VAPA, VAPB, DYNLL1, AKAP1, RPS6, RPL27A, PRKAR2B, PRKAR2A, PRKAR1B, PRKAR1A, PRKACA, HSP90AB1, HS
Protein Size: 351

Poids moléculaire: 40 kDa

ID gène: 5567

NCBI Accession: NM_002731, NP_002722

UniProt: P22694

Pathways: AMPK Signaling, Signalisation Hedgehog, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Lipid Metabolism