VPS36 anticorps (N-Term)

N° du produit ABIN2786923

Détail du produit anti-VPS36 anticorps

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Boeuf (Vache), Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS36 est non-conjugé

Application: Western Blotting (WB)

Séquence: SNKEPGPFQS SKNSYIRLSF KEHGQIEFYR RLSEEMTQRR WETVPVSQSL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against Vps36. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 386 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur VPS36

Antigène: VPS36 (Vacuolar Protein Sorting 36 (VPS36))

Autre désignation: Vps36 (VPS36 Produits)

Synonymes: anticorps C13orf9, anticorps EAP45, anticorps 1700010A24Rik, anticorps 2210415M20Rik, anticorps 2810408E15Rik, anticorps Eap45, anticorps RGD1309754, anticorps fj33d07, anticorps wu:fj33d07, anticorps zgc:55965, anticorps MUG13.23, anticorps MUG13_23, anticorps VPS36, anticorps CG10711, anticorps Dmel\\CG10711, anticorps l(3)L5212, anticorps vps36, anticorps DDBDRAFT_0205116, anticorps DDBDRAFT_0234028, anticorps DDB_0205116, anticorps DDB_0234028, anticorps vacuolar protein sorting 36 homolog, anticorps vacuolar protein sorting 36, anticorps vacuolar protein sorting-associated protein 36, anticorps vacuolar protein sorting 36 homolog (S. cerevisiae), anticorps EAP30/Vps36 family protein, anticorps Vacuolar protein sorting 36, anticorps vacuolar protein sorting 36 homolog L homeolog, anticorps vacuolar protein-sorting-associated protein 36, anticorps ESCRT II complex subunit Vps36, anticorps VPS36, anticorps Vps36, anticorps LACBIDRAFT_399634, anticorps vps36, anticorps AT5G04920, anticorps vps36.L, anticorps PTRG_11114, anticorps MCYG_02556, anticorps MGYG_08257, anticorps TERG_05645, anticorps Tsp_04139

Sujet: Vps36 is a component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3.
Alias Symbols: 1700010A24Rik, 2210415M20Rik, 2810408E15Rik, Eap45
Protein Interaction Partner: Ubc,
Protein Size: 386

Poids moléculaire: 42 kDa

ID gène: 70160

NCBI Accession: NM_027338, NP_081614

UniProt: Q91XD6