SHC3 anticorps (Middle Region)

N° du produit ABIN2786992

Détail du produit anti-SHC3 anticorps

Antigène: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHC3 est non-conjugé

Application: Western Blotting (WB)

Séquence: RLKPRPHAPD TAQFAGKEQT YYQGRHLGDT FGEDWQQTPL RQGSSDIYST

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SHC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SHC3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 594 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SHC3

Antigène: SHC3 (SHC (Src Homology 2 Domain Containing) Transforming Protein 3 (SHC3))

Autre désignation: SHC3 (SHC3 Produits)

Sujet: SHC3 is a signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. SHC3 is involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
Alias Symbols: N-Shc, NSHC, SHCC, RAI
Protein Interaction Partner: KRT40, KRT31, GOLGA2, ERBB3, ERBB2, EGFR, SH3GL3, ARHGAP32, NTRK2, NTRK1, RET, FLT4, AXL, GRB2, ALK, APP,
Protein Size: 594

Poids moléculaire: 64 kDa

ID gène: 53358

NCBI Accession: NM_016848, NP_058544

UniProt: Q92529

Pathways: Signalisation RTK, EGFR Signaling Pathway, Neurotrophin Signaling Pathway