PI4K2B anticorps (N-Term)

N° du produit ABIN2787116

Détail du produit anti-PI4K2B anticorps

Antigène: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PI4K2B est non-conjugé

Application: Western Blotting (WB)

Séquence: EDPEFADIVL KAEQAIEIGV FPERISQGSS GSYFVKDSKR NIIGVFKPKS

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against Pi4k2b. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide corresponding to a region of Mouse

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 469 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PI4K2B

Antigène: PI4K2B (Phosphatidylinositol 4-Kinase Type 2 beta (PI4K2B))

Autre désignation: Pi4k2b (PI4K2B Produits)

Synonymes: anticorps GB16449, anticorps pi4kiib, anticorps pik42b, anticorps PI4KIIB, anticorps PIK42B, anticorps 2610042N09Rik, anticorps 4933409G22Rik, anticorps zgc:158305, anticorps uncharacterized LOC725812, anticorps phosphatidylinositol 4-kinase type 2 beta L homeolog, anticorps phosphatidylinositol 4-kinase type 2 beta, anticorps LOC725812, anticorps pi4k2b.L, anticorps PI4K2B, anticorps pi4k2b, anticorps Pi4k2b

Sujet: Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Alias Symbols: 2610042N09Rik, 4933409G22Rik
Protein Size: 469

Poids moléculaire: 52 kDa

ID gène: 67073

NCBI Accession: NM_025951, NP_080227

UniProt: Q8CBQ5

Pathways: Inositol Metabolic Process