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TXNIP anticorps (Middle Region)

TXNIP Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2787922
  • Antigène Voir toutes TXNIP Anticorps
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Épitope
    • 16
    • 14
    • 9
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 63
    • 47
    • 32
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cobaye
    Hôte
    • 72
    • 5
    Lapin
    Clonalité
    • 63
    • 14
    Polyclonal
    Conjugué
    • 32
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TXNIP est non-conjugé
    Application
    • 59
    • 32
    • 16
    • 14
    • 14
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VDYWVKAFLD RPSQPTQETK KNFEVVDLVD VNTPDLMAPV SAKKEKKVSC
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
    Attributs du produit
    This is a rabbit polyclonal antibody against TXNIP. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human TXNIP
    Top Product
    Discover our top product TXNIP Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 391 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TXNIP (Thioredoxin Interacting Protein (TXNIP))
    Autre désignation
    TXNIP (TXNIP Produits)
    Synonymes
    anticorps EST01027, anticorps HHCPA78, anticorps THIF, anticorps VDUP1, anticorps Gm348, anticorps Trf3, anticorps TBP2, anticorps TRF3, anticorps 1200008J08Rik, anticorps AA682105, anticorps Hyplip1, anticorps Tbp-2, anticorps Vdup1, anticorps sb:cb368, anticorps txnip, anticorps thioredoxin interacting protein, anticorps TATA box binding protein like 2, anticorps TATA-box binding protein like 2, anticorps thioredoxin interacting protein L homeolog, anticorps thioredoxin interacting protein a, anticorps TXNIP, anticorps Tbpl2, anticorps TBPL2, anticorps Txnip, anticorps txnip.L, anticorps txnip, anticorps txnipa
    Sujet
    TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
    Alias Symbols: EST01027, HHCPA78, THIF, VDUP1
    Protein Interaction Partner: UBC, DDIT4, ECD, TXN, TP53, SMURF2, UL49, ITCH, ELAVL1, FHL1, ZBTB32, ZBTB16, SCEL, HDAC1, TXNRD1, KPNA2,
    Protein Size: 391
    Poids moléculaire
    44 kDa
    ID gène
    10628
    NCBI Accession
    NM_006472, NP_006463
    UniProt
    Q9H3M7
    Pathways
    Protein targeting to Nucleus, Platelet-derived growth Factor Receptor Signaling, Inflammasome
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