TNFRSF4 anticorps (Middle Region)
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- Antigène Voir toutes TNFRSF4 Anticorps
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
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Épitope
- Middle Region
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Reactivité
- Humain, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TNFRSF4 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GKHTLQPASN SSDAICEDRD PPATQPQETQ GPPARPITVQ PTEAWPRTSQ
- Homologie
- Human: 100%, Pig: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against TNFRSF4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human TNFRSF4
- Top Product
- Discover our top product TNFRSF4 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 277 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TNFRSF4 (Tumor Necrosis Factor Receptor Superfamily, Member 4 (TNFRSF4))
- Autre désignation
- TNFRSF4 (TNFRSF4 Produits)
- Synonymes
- anticorps TNFRSF4, anticorps ACT35, anticorps CD134, anticorps Ly-70, anticorps Ox40, anticorps TXGP1L, anticorps Txgp1, anticorps OX40, anticorps TNF receptor superfamily member 4, anticorps tumor necrosis factor receptor superfamily, member 4, anticorps TNFRSF4, anticorps Tnfrsf4
- Sujet
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.
Alias Symbols: ACT35, CD134, OX40, TXGP1L
Protein Interaction Partner: TRAF4, TRAF5, TRAF3, TRAF2, TRAF1, TNFRSF9, SIVA1, TNFSF4,
Protein Size: 277 - Poids moléculaire
- 27 kDa
- ID gène
- 7293
- NCBI Accession
- NM_003327, NP_003318
- UniProt
- P43489
- Pathways
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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