PSMF1 anticorps (Middle Region)
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- Antigène Voir toutes PSMF1 Anticorps
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Lapin, Cheval, Cobaye
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PSMF1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DYIDAEHLGD FHRTYKNSEE LRSRIVSGII TPIHEQWEKA NVSSPHREFP
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PSMF1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PSMF1
- Top Product
- Discover our top product PSMF1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 271 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Autre désignation
- PSMF1 (PSMF1 Produits)
- Synonymes
- anticorps PI31, anticorps AW048666, anticorps BC012260, anticorps zgc:92785, anticorps proteasome inhibitor subunit 1, anticorps proteasome (prosome, macropain) inhibitor subunit 1, anticorps PSMF1, anticorps Psmf1, anticorps psmf1
- Sujet
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Alias Symbols: PI31
Protein Interaction Partner: FBXO7, SHFM1, UBC, BEND7, RHOXF2, KHDRBS3, PAK7, LDOC1, RBFOX2, PSMA7, DVL3, RALYL, RBFOX1, QKI, CD2BP2, CUL1, PSMA2, MIEF2, CCDC85B, RNF126, PDLIM7, HOOK2, NUDT21, CTBP2, TRAF2, MAGEA11, RBMX,
Protein Size: 271 - Poids moléculaire
- 30 kDa
- ID gène
- 9491
- NCBI Accession
- NM_006814, NP_006805
- UniProt
- Q92530
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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