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MRGPRX2 anticorps (Middle Region)

MRGPRX2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788260
  • Antigène Voir toutes MRGPRX2 Anticorps
    MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
    Épitope
    • 9
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 32
    • 2
    • 1
    Humain
    Hôte
    • 27
    • 5
    Lapin
    Clonalité
    • 29
    • 3
    Polyclonal
    Conjugué
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    Cet anticorp MRGPRX2 est non-conjugé
    Application
    • 20
    • 18
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VCVLLWALSL LLSILEGKFC GFLFSDGDSG WCQTFDFITA AWLIFLFMVL
    Homologie
    Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against MRGPRX2. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human MRGPRX2
    Top Product
    Discover our top product MRGPRX2 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 330 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))
    Autre désignation
    MRGPRX2 (MRGPRX2 Produits)
    Synonymes
    anticorps MRGX2, anticorps G370024M05Rik, anticorps MrgB10, anticorps Mrgprb10, anticorps MrgB1, anticorps Mrgprb1, anticorps MAS related GPR family member X2, anticorps MAS-related GPR, member X2, anticorps MRGPRX2, anticorps Mrgprx2
    Sujet
    MRGPRX2 is an orphan receptor. It probably involved in the function of nociceptive neurons. It also may regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca2+ but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
    Alias Symbols: MRGX2
    Protein Interaction Partner: CORT,
    Protein Size: 330
    Poids moléculaire
    37 kDa
    ID gène
    117194
    NCBI Accession
    NM_054030, NP_473371
    UniProt
    Q96LB1
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