CYP24A1 anticorps (C-Term)

N° du produit ABIN2788352

Détail du produit anti-CYP24A1 anticorps

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP24A1 est non-conjugé

Application: Western Blotting (WB)

Séquence: QVLGSSEDNF EDSSQFRPER WLQEKEKINP FAHLPFGVGK RMCIGRRLAE

Homologie: Dog: 79%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against CYP24A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP24A1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 514 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CYP24A1

Antigène: CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))

Autre désignation: CYP24A1 (CYP24A1 Produits)

Sujet: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CP24, CYP24, MGC126273, MGC126274, P450-CC24, HCAI
Protein Interaction Partner: Dlg4, UBC,
Protein Size: 514

Poids moléculaire: 55 kDa

ID gène: 1591

NCBI Accession: NM_000782, NP_000773

UniProt: Q07973

Pathways: Metabolism of Steroid Hormones and Vitamin D