Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

HLA-DMA anticorps (N-Term)

HLA-DMA Reactivité: Humain, Rat, Lapin, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2788737
  • Antigène Voir toutes HLA-DMA Anticorps
    HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
    Épitope
    • 6
    • 4
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Rat, Lapin, Chien
    Hôte
    • 14
    • 2
    • 2
    Lapin
    Clonalité
    • 15
    • 3
    Polyclonal
    Conjugué
    • 13
    • 3
    • 1
    • 1
    Cet anticorp HLA-DMA est non-conjugé
    Application
    • 12
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    GLSEAYDEDQ LFFFDFSQNT RVPRLPEFAD WAQEQGDAPA ILFDKEFCEW
    Homologie
    Dog: 77%, Human: 100%, Rabbit: 82%, Rat: 86%
    Attributs du produit
    This is a rabbit polyclonal antibody against HLA-DMA. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-DMA
    Top Product
    Discover our top product HLA-DMA Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 261 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    HLA-DMA (Major Histocompatibility Complex, Class II, DM alpha (HLA-DMA))
    Autre désignation
    HLA-DMA (HLA-DMA Produits)
    Synonymes
    anticorps RT1.Ma, anticorps RT1.DMa, anticorps HLA-DMA, anticorps H-2Ma, anticorps H2-Ma, anticorps D6S222E, anticorps DMA, anticorps HLADM, anticorps RING6, anticorps RT1 class II, locus DMa, anticorps SLA-DM alpha chain, anticorps major histocompatibility complex, class II, DM alpha, anticorps histocompatibility 2, class II, locus DMa, anticorps RT1-DMa, anticorps SLA-DMA, anticorps DLA-DMA, anticorps H2-DMa, anticorps HLA-DMA
    Sujet
    HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.
    Alias Symbols: D6S222E, DMA, HLADM, RING6
    Protein Interaction Partner: B3GAT1, U2AF2, RUNX1, UBC, CD82, HLA-DRB1, HLA-DOA, HLA-DRA, HLA-DMB, CD74,
    Protein Size: 261
    Poids moléculaire
    29 kDa
    ID gène
    3108
    NCBI Accession
    NM_006120, NP_006111
    UniProt
    Q31604
    Pathways
    Cancer Immune Checkpoints
Vous êtes ici:
Support technique