TSEN2 anticorps (C-Term)

N° du produit ABIN2789135

Détail du produit anti-TSEN2 anticorps

Antigène: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Épitope: C-Term

Reactivité: Humain, Chien, Cheval, Lapin, Boeuf (Vache), Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSEN2 est non-conjugé

Application: Western Blotting (WB)

Séquence: LRRPLSWKSL AALSRVSVNV SKELMLCYLI KPSTMTDKEM ESPECMKRIK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TSEN2. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 465 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TSEN2

Antigène: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Autre désignation: TSEN2 (TSEN2 Produits)

Synonymes: anticorps AU067695, anticorps RGD1309946, anticorps PCH2B, anticorps SEN2, anticorps SEN2L, anticorps tRNA splicing endonuclease subunit 2, anticorps TSEN2, anticorps Tsen2

Sujet: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L
Protein Interaction Partner: TSEN54, UBC, TBC1D2, PRPF39, POLD3, TBC1D4, TRIP10, USP8, POLD1, Clp1, RANBP10, TSEN15, TSEN34,
Protein Size: 465

Poids moléculaire: 51 kDa

ID gène: 80746

NCBI Accession: NM_025265, NP_079541

UniProt: Q8NCE0

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha