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CD33 anticorps (N-Term)

CD33 Reactivité: Humain, Boeuf (Vache), Cheval WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2789356
  • Antigène Voir toutes CD33 Anticorps
    CD33
    Épitope
    • 16
    • 16
    • 13
    • 9
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 168
    • 35
    • 15
    • 13
    • 7
    • 6
    • 2
    Humain, Boeuf (Vache), Cheval
    Hôte
    • 94
    • 80
    Lapin
    Clonalité
    • 89
    • 84
    • 1
    Polyclonal
    Conjugué
    • 59
    • 16
    • 13
    • 12
    • 10
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD33 est non-conjugé
    Application
    • 107
    • 102
    • 40
    • 30
    • 26
    • 26
    • 23
    • 22
    • 16
    • 13
    • 11
    • 9
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG
    Homologie
    Cow: 79%, Horse: 79%, Human: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against CD33. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product CD33 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 364 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    CD33
    Autre désignation
    CD33 (CD33 Produits)
    Synonymes
    anticorps SIGLEC-3, anticorps SIGLEC3, anticorps p67, anticorps Siglec-3, anticorps gp67, anticorps CD33 molecule, anticorps CD33 antigen, anticorps CD33, anticorps Cd33
    Sujet
    CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia (in vitro).
    Alias Symbols: FLJ00391, SIGLEC-3, SIGLEC3, p67
    Protein Interaction Partner: KRT40, KRT31, HERC3, UBC, CBL, SRC, PTPN6, PTPN11,
    Protein Size: 364
    Poids moléculaire
    38 kDa
    ID gène
    945
    NCBI Accession
    NM_001772, NP_001763
    UniProt
    P20138
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