IKKi/IKKe anticorps (N-Term)

N° du produit ABIN2789403

Détail du produit anti-IKKi/IKKe anticorps

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Épitope: N-Term

Reactivité: Humain, Rat, Cobaye, Boeuf (Vache), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKKi/IKKe est non-conjugé

Application: Western Blotting (WB)

Séquence: AGAIAGAQRR ENGPLEWSYT LPITCQLSLG LQSQLVPILA NILEVEQAKC

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 93%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against IKBKE. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 631 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur IKKi/IKKe

Antigène: IKKi/IKKe (IKBKE) (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Autre désignation: IKBKE (IKBKE Produits)

Synonymes: anticorps zgc:100844, anticorps IKBKE, anticorps MGC130907, anticorps IKK-E, anticorps IKK-i, anticorps IKKE, anticorps IKKI, anticorps AW558201, anticorps IKKepsilon, anticorps Ikki, anticorps inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon, anticorps inhibitor of nuclear factor kappa B kinase subunit epsilon, anticorps inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog, anticorps inhibitor of kappaB kinase epsilon, anticorps IKBKE, anticorps ikbke, anticorps ikbke.L, anticorps Ikbke

Sujet: IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30 % of breast carcinomas and breast cancer cell lines.
Alias Symbols: IKK-i, IKKE, IKKI, KIAA0151, MGC125294, MGC125295, MGC125297, IKK-E
Protein Interaction Partner: CD209, TRIM6, UBC, TRAF3, NMRAL1, DDX58, MAFB, MYD88, IKBKB, HSP90AA1, DDX3X, CYLD, BIRC3, BIRC2, AZI2, TRAF3IP2, TANK, TBKBP1, IKBKE, IKBKG, TRAF2, RNF11, NFKBIA, TOPORS, SUMO1, SUMO2, SUMO3, TRIM27, PML, MAVS, TBK1, MBP, TNIP1, TAX1BP1, TNFAIP3, IRF3, C
Protein Size: 631

Poids moléculaire: 69 kDa

ID gène: 9641

NCBI Accession: NM_001193321, NP_001180250

UniProt: Q3B754

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades