TP53I3 anticorps (C-Term)

N° du produit ABIN2789866

Détail du produit anti-TP53I3 anticorps

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Épitope: C-Term

Reactivité: Humain, Lapin, Boeuf (Vache), Chien, Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53I3 est non-conjugé

Application: Western Blotting (WB)

Séquence: GFNYKKEDFS EATLKFTKGA GVNLILDCIG GSYWEKNVNC LALDGRWVLY

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 86%

Attributs du produit: This is a rabbit polyclonal antibody against TP53I3. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 332 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TP53I3

Antigène: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Autre désignation: TP53I3 (TP53I3 Produits)

Synonymes: anticorps MGC82892, anticorps MGC146409, anticorps PIG3, anticorps tumor protein p53 inducible protein 3, anticorps tumor protein p53 inducible protein 3 S homeolog, anticorps Tp53I3, anticorps quinone oxidoreductase PIG3, anticorps TP53I3, anticorps tp53i3.S, anticorps tp53i3, anticorps tp53I3

Sujet: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
Alias Symbols: PIG3
Protein Interaction Partner: TLDC1, PLK1, UBC, TP53BP1, H2AFX, EEF1G, UBR1, FUNDC2, UNC119, TP53,
Protein Size: 332

Poids moléculaire: 35 kDa

ID gène: 9540

NCBI Accession: NM_004881, NP_004872

UniProt: Q53FA7

Pathways: Signalisation p53