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PTPN21 anticorps (C-Term)

PTPN21 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2790277
  • Antigène Voir toutes PTPN21 Anticorps
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    Épitope
    • 15
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 28
    • 21
    • 20
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Chien
    Hôte
    • 29
    Lapin
    Clonalité
    • 29
    Polyclonal
    Conjugué
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTPN21 est non-conjugé
    Application
    • 29
    • 13
    • 13
    • 12
    • 9
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Séquence
    FWQMVWEQGI AIIAMVTAEE EGGREKSFRY WPRLGSRHNT VTYGRFKITT
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against PTPN21. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human PTPN21
    Top Product
    Discover our top product PTPN21 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 1174 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
    Autre désignation
    PTPN21 (PTPN21 Produits)
    Synonymes
    anticorps PTPD1, anticorps PTPRL10, anticorps Ptp2E, anticorps protein tyrosine phosphatase, non-receptor type 21, anticorps PTPN21, anticorps Ptpn21
    Sujet
    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.
    Alias Symbols: PTPD1, PTPRL10
    Protein Interaction Partner: KIF1C, AKAP1, TEC, BMX, SRC,
    Protein Size: 1174
    Poids moléculaire
    133 kDa
    ID gène
    11099
    NCBI Accession
    NM_007039, NP_008970
    UniProt
    Q16825
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