YOD1 anticorps (N-Term)

N° du produit ABIN2790891

Détail du produit anti-YOD1 anticorps

Antigène: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YOD1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VPQSEAGTKA GPAGGRPADT MWRVRCKAKG GTHLLQGLSS RTRLRELQGQ

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against Yod1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Yod1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur YOD1

Antigène: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Autre désignation: Yod1 (YOD1 Produits)

Synonymes: anticorps DUBA8, anticorps OTUD2, anticorps PRO0907, anticorps hshin7, anticorps wu:fe01a10, anticorps zgc:112182, anticorps 9930028C20Rik, anticorps Hshin7, anticorps YOD1 deubiquitinase, anticorps YOD1 deubiquitinase L homeolog, anticorps YOD1, anticorps Yod1, anticorps yod1.L, anticorps yod1

Sujet: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. Yod1 may act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Ubiquitin moieties on substrates may present a steric impediment to the threading process when the substrate is transferred to the VCP pore and threaded through VCP's axial channel. Yod1 mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. It is able to cleave both polyubiquitin and di-ubiquitin.
Alias Symbols: 9930028C20Rik, Hshin7
Protein Size: 343

Poids moléculaire: 37 kDa

ID gène: 226418

NCBI Accession: NM_178691, NP_848806

UniProt: Q8CB27

Pathways: ER-Nucleus Signaling