SLX1A/GIYD2 anticorps (N-Term)

N° du produit ABIN2791914

Détail du produit anti-SLX1A/GIYD2 anticorps

Antigène: SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))

Épitope: N-Term

Reactivité: Humain, Souris, Cheval, Boeuf (Vache), Chien, Cobaye, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLX1A/GIYD2 est non-conjugé

Application: Western Blotting (WB)

Séquence: FFGVYLLYCL NPRYRGRVYV GFTVNTARRV QQHNGGRKKG GAWRTSGRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SLX1B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SLX1B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SLX1A/GIYD2

Antigène: SLX1A/GIYD2 (SLX1B) (SLX1 Structure-Specific Endonuclease Subunit Homolog B (SLX1B))

Autre désignation: SLX1B (SLX1B Produits)

Synonymes: anticorps 1110030E23Rik, anticorps 2410170E21Rik, anticorps 4833422P03Rik, anticorps AI853643, anticorps Giyd1, anticorps Giyd2, anticorps LRRGT00058, anticorps RGD1311568, anticorps GIYD2, anticorps SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae), anticorps SLX1 homolog B, structure-specific endonuclease subunit, anticorps Slx1b, anticorps SLX1B

Sujet: This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication, this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
Protein Interaction Partner: SLX4, THAP11, DUSP10, TUBA1B, LOC344382, EME1, SLX4IP, SLIRP, MUS81, GEMIN6, PAGR1, FKBP10, GEMIN4, DDX20, TIMM17B, PSME3, SLC25A13, HUWE1, PSMD6, CUL1, UQCRC2, SMN1, S100A8, RAN, PSMD11, PSMB5, PSMB3, PSMB2, PSMB1, PSMA7, PSMA6, PSMA5, PSMA4, PSMA3, PSMA
Protein Size: 275

Poids moléculaire: 30 kDa

ID gène: 79008

UniProt: Q9BQ83

Pathways: Réparation de l'ADN