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YWHAE anticorps (Middle Region)

YWHAE Reactivité: Souris, Poisson zèbre (Danio rerio), Cobaye, Chien WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792142
  • Antigène Voir toutes YWHAE Anticorps
    YWHAE (14-3-3 epsilon (YWHAE))
    Épitope
    • 15
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 52
    • 37
    • 34
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Souris, Poisson zèbre (Danio rerio), Cobaye, Chien
    Hôte
    • 48
    • 4
    • 1
    Lapin
    Clonalité
    • 41
    • 12
    Polyclonal
    Conjugué
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp YWHAE est non-conjugé
    Application
    • 41
    • 17
    • 13
    • 13
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    ELDTLSEESY KDSTLIMQLL RDNLTLWTSD MQGDGEEQNK EALQDVEDEN
    Homologie
    Dog: 100%, Guinea Pig: 100%, Mouse: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against YWHAE. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the middle region of human YWHAE
    Top Product
    Discover our top product YWHAE Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 255 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tak, Jang, Kim, Park, Suk, Yoon, Ahn, Lee, Joe: "14-3-3epsilon inhibits MK5-mediated cell migration by disrupting F-actin polymerization." dans: Cellular signalling, Vol. 19, Issue 11, pp. 2379-87, (2007) (PubMed).

  • Antigène
    YWHAE (14-3-3 epsilon (YWHAE))
    Autre désignation
    YWHAE (YWHAE Produits)
    Synonymes
    anticorps 14-3-3, anticorps 14-3-3 epsilon, anticorps 14-3-3-e, anticorps 14-3-3-epsilon, anticorps 14-3-30epsilon, anticorps 14-3-3EPSILON, anticorps 14-3-3e, anticorps 14-3-3omicron, anticorps 1433epsilon, anticorps 143E_DROME, anticorps CG31196, anticorps CT24092, anticorps D14-3-3e, anticorps D14-3-3epsilon, anticorps Dmel\\CG31196, anticorps EK3-5, anticorps PAR-5, anticorps PAR5, anticorps Par-5, anticorps SR3-9, anticorps Su(Raf)3B, anticorps anon-WO0172774.141, anticorps anon-WO02059370.52, anticorps d14-3-3epsilon, anticorps eps, anticorps l(3)j2B10, anticorps par-5, anticorps 14-3-3epsilon, anticorps kcip-1, anticorps mdcr, anticorps mds, anticorps LOC581376, anticorps Ywhae, anticorps ACYPI002517, anticorps YWHAE, anticorps 14-3-3E, anticorps KCIP-1, anticorps MDCR, anticorps MDS, anticorps AU019196, anticorps fe38c12, anticorps wu:fb48f06, anticorps wu:fe38c12, anticorps wu:fi22e10, anticorps ywhae, anticorps zgc:55377, anticorps zgc:77062, anticorps CG31196 gene product from transcript CG31196-RD, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon, anticorps 14-3-3 epsilon, anticorps 14-3-3 epsilon protein, anticorps 14-3-3 protein epsilon, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1, anticorps 14-3-3epsilon, anticorps ywhae, anticorps LOC581376, anticorps Ywhae, anticorps HCAG_04173, anticorps PTRG_02836, anticorps PTRG_04459, anticorps UREG_07864, anticorps YWHAE, anticorps ywhae.S, anticorps ywhae1
    Sujet
    YWHAE is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. YWHAE binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. The binding generally results in the modulation of the activity of the binding partner.This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100 % identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: 14-3-3E, FLJ45465, KCIP-1, MDCR, MDS
    Protein Interaction Partner: DTL, HUWE1, FAM53C, FBXW11, SORBS2, UBC, ABL1, GRB10, SIK2, CEP57, SIK3, TP53, IRS4, CBL, TUBB2A, TWF2, PROSC, FERMT2, PDIA4, RAP1GDS1, PTMA, PPP1R2, PDHB, PAK2, PAFAH1B2, YWHAH, XPO1, VCL, GSS, G6PD, EIF5, TBCB, CAPNS1, CAPN2, ALDH7A1, ATIC, ASNS, SCPEP1
    Protein Size: 255
    Poids moléculaire
    29 kDa
    ID gène
    7531
    NCBI Accession
    NM_006761, NP_006752
    UniProt
    P62258
    Pathways
    Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase
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