STAT3 anticorps (Middle Region)

N° du produit ABIN2792239

Détail du produit anti-STAT3 anticorps

Antigène: STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Porc, Chien, Cheval, Mouton, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FGKYCRPESQ EHPEADPGSA APYLKTKFIC VTPTTCSNTI DLPMSPRTLD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Attributs du produit: This is a rabbit polyclonal antibody against STAT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human STAT3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 770 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-STAT3 (ABIN2792239)

Suen, Uddin, Prow, Bowen, Hall, Bielefeldt-Ohmann: "Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits." dans: Virology, Vol. 494, pp. 1-14, (2016) (PubMed).

Détails sur STAT3

Antigène: STAT3 (Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3))

Autre désignation: STAT3 (STAT3 Produits)

Synonymes: anticorps 1110034C02Rik, anticorps AW109958, anticorps Aprf, anticorps APRF, anticorps HIES, anticorps Xstat3, anticorps aprf, anticorps hies, anticorps stat3, anticorps wu:fc15d02, anticorps wu:fl59g06, anticorps z-Stat3, anticorps signal transducer and activator of transcription 3, anticorps signal transduction and activation of transcription 3, anticorps signal transducer and activator of transcription 3, gene 1 L homeolog, anticorps signal transducer and activator of transcription 3 (acute-phase response factor), anticorps STAT3, anticorps stat3, anticorps Stat3, anticorps stat3.1.L

Sujet: STAT3 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act a
Alias Symbols: APRF, FLJ20882, MGC16063, HIES
Protein Interaction Partner: MTOR, GADD45A, BMX, BLK, UBC, SYK, LMO2, SRI, HIC1, GNB2, USP22, RELA, COPS5, BRD4, ADRB2, PSMG3, TBCD, TBC1D15, PUS7, LUC7L2, ARFIP1, IVNS1ABP, MSH2, BMH1, SIN3A, EGFR, PIAS3, HDAC3, SRC, LYN, JAK3, JAK2, HES5, TRIM28, HES1, HCK, FYN, FGR, HNRNPM, SULT2A
Protein Size: 770

Poids moléculaire: 88 kDa

ID gène: 6774

NCBI Accession: NM_139276, NP_644805

UniProt: P40763

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Stem Cell Maintenance, Hepatitis C, Protein targeting to Nucleus, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor