RFX1 anticorps (C-Term)

N° du produit ABIN2792556

Détail du produit anti-RFX1 anticorps

Antigène: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Porc, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RFX1 est non-conjugé

Application: Western Blotting (WB)

Séquence: ESEDELPQDI SLAAGGESPA LGPETLEPPA KLARTDARGL FVQALPSS

Réactivité croisée: Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 92%, Pig: 92%, Rat: 92%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against RFX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RFX1

Information d'application

Indications d'application: WB Suggested Anti-RFX1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:312500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 979 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RFX1

Antigène: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Autre désignation: RFX1 (RFX1 Produits)

Synonymes: anticorps EFC, anticorps RFX, anticorps AI047719, anticorps AI385641, anticorps zgc:162914, anticorps regulatory factor X1, anticorps regulatory factor X, 1 (influences HLA class II expression), anticorps regulatory factor X, 1a (influences HLA class II expression), anticorps RFX1, anticorps Rfx1, anticorps rfx1a

Sujet: RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX1 is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: EF-C, EFC, RFX
Protein Interaction Partner: SOX2, SMAD9, SMAD4, SMAD1, NOTCH1, Cebpb, NCOA3, HDAC1, NFIC, NFIB, TADA3, RFX3, MAGED1, ABL1, NFIX, HMGB1, HIVEP2, RFX2, ADD1,
Protein Size: 979

Poids moléculaire: 105 kDa

ID gène: 5989

NCBI Accession: NM_002918, NP_002909

UniProt: P22670