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NR3C2 anticorps (C-Term)

NR3C2 Reactivité: Humain, Rat, Souris, Cheval, Boeuf (Vache) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792564
  • Antigène Voir toutes NR3C2 Anticorps
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Épitope
    • 16
    • 15
    • 15
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 57
    • 45
    • 29
    • 17
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Humain, Rat, Souris, Cheval, Boeuf (Vache)
    Hôte
    • 70
    • 5
    Lapin
    Clonalité
    • 69
    • 6
    Polyclonal
    Conjugué
    • 27
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Cet anticorp NR3C2 est non-conjugé
    Application
    • 72
    • 39
    • 39
    • 20
    • 14
    • 12
    • 10
    • 9
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    VSDLLEFCFY TFRESHALKV EFPAMLVEII SDQLPKVESG NAKPLYFHRK
     Réactivité croisée
    Poulet, Humain, Souris, Rat (Rattus)
    Homologie
    Cow: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against NR3C2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C terminal region of human NR3C2
    Top Product
    Discover our top product NR3C2 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-NR3C2 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:12500
    Positive Control: PANC1 cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 867 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    NR3C2 (Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2))
    Autre désignation
    NR3C2 (NR3C2 Produits)
    Synonymes
    anticorps mr, anticorps si:ch211-189l17.1, anticorps LOC100302443, anticorps NR3C2, anticorps LOC443144, anticorps MLR, anticorps MR, anticorps MCR, anticorps NR3C2VIT, anticorps Mlr, anticorps mlr, anticorps nuclear receptor subfamily 3, group C, member 2, anticorps nuclear receptor subfamily 3 group C member 2, anticorps mineralocorticoid receptor, anticorps nuclear receptor subfamily 3 group C member 2 L homeolog, anticorps nr3c2, anticorps NR3C2, anticorps LOC443144, anticorps Nr3c2, anticorps nr3c2.L
    Sujet
    NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
    Alias Symbols: MR, MCR, MLR, FLJ41052, NR3C2VIT, MGC133092, NR3C2
    Protein Interaction Partner: RABAC1, RXRA, HSP90AA1, ACSL1, UBC, SRC, PPP5C, PPID, FKBP5, FKBP4, STUB1, AIP, TRIM24, NRIP1, DNAJC7, CAND1, SUMO1, UBE2I, EIF3I, PROX1, PIAS1, PIAS3, HSPA4, PTGES3, AR, NR3C1, ACTA1, ACTG1,
    Protein Size: 867
    Poids moléculaire
    94 kDa
    ID gène
    4306
    NCBI Accession
    NM_001166104, NP_001159576
    UniProt
    B0ZBF5
    Pathways
    ACE Inhibitor Pathway, Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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