GTF2H2 anticorps (N-Term)
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- Antigène Voir toutes GTF2H2 Anticorps
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
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Épitope
- N-Term
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Reactivité
- Humain, Souris, Rat, Cheval, Poisson zèbre (Danio rerio), Chien
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp GTF2H2 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- DILFKAKRKR VFEHHGQVRL GMMRHLYVVV DGSRTMEDQD LKPNRLTCTL
- Réactivité croisée
- Boeuf (Vache), Chien, Poulet, Humain, Souris, Rat (Rattus)
- Homologie
- Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
- Attributs du produit
- This is a rabbit polyclonal antibody against GTF2H2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H2
- Top Product
- Discover our top product GTF2H2 Anticorps primaire
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- Indications d'application
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WB Suggested Anti-GTF2H2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Commentaires
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Antigen size: 395 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
- Autre désignation
- GTF2H2 / BTF2P44 (GTF2H2 Produits)
- Synonymes
- anticorps 44kDa, anticorps BTF2 p44, anticorps BTF2-p44, anticorps Btf2p44, anticorps p44, anticorps BTF2, anticorps BTF2P44, anticorps T-BTF2P44, anticorps TFIIH, anticorps general transcription factor II H, polypeptide 2, anticorps general transcription factor IIH subunit 2, anticorps general transcription factor IIH, polypeptide 2, 44kDa, anticorps Gtf2h2, anticorps GTF2H2
- Sujet
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GTF2H2 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. GTF2H2 is the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene.This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This gene is within the telomeric copy of the duplication. Deletion of this gene sometimes accompanies deletion of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients but it is unclear if deletion of this gene contributes to the SMA phenotype. This gene encodes the 44 kDa subunit of RNA polymerase II transcription initiation factor IIH which is involved in basal transcription and nucleotide excision repair. Transcript variants for this gene have been described, but their full length nature has not been determined. A second copy of this gene within the centromeric copy of the duplication has been described in the literature. It is reported to be different by either two or four base pairs, however, no sequence data is currently available for the centromeric copy of the gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-15 BM083743.1 1-15 16-1121 AF078847.1 1-1106 1122-1537 BG283896.1 128-543 1538-1951 AC044797.5 132110-132523 c
Alias Symbols: BTF2, BTF2P44, MGC102806, T-BTF2P44, TFIIH, p44
Protein Interaction Partner: UBC, CDK7, GTF2H5, GTF2H1, SRA1, GTF2H4, GTF2H3, UBD, COPS2, ERCC3, ERCC8, ERCC2, AR, MNAT1, CCNH,
Protein Size: 395 - Poids moléculaire
- 44 kDa
- ID gène
- 2966
- NCBI Accession
- NM_001515, NP_001506
- UniProt
- Q13888
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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