NFATC3 anticorps (N-Term)

N° du produit ABIN2792685

Détail du produit anti-NFATC3 anticorps

Antigène: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFATC3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AVFPFQYCVE TDIPLKTRKT SEDQAAILPG KLELCSDDQG SLSPARETSI

Réactivité croisée: Humain, Souris, Rat (Rattus)

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against NFATC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC3

Information d'application

Indications d'application: WB Suggested Anti-NFATC3 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:62500
Positive Control: Hela cell lysate.
Immunohistochemistry with Thymus tissue at an antibody concentration of 5 µg/mL using anti-NFATC3 antibody (ABIN504679).
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1068 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NFATC3

Antigène: NFATC3 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3))

Autre désignation: NFAT4 / NFATC3 (NFATC3 Produits)

Synonymes: anticorps NFATC3, anticorps NFATx, anticorps nf-at, anticorps nfat4, anticorps nfatx, anticorps C80703, anticorps D8Ertd281e, anticorps NFAT4, anticorps NFATX, anticorps nuclear factor of activated T-cells 3, anticorps nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3, anticorps nuclear factor of activated T-cells 3 S homeolog, anticorps NFATC3, anticorps nfatc3, anticorps Nfatc3, anticorps nfatc3.S

Sujet: NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes.The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Four transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: NFAT4, NFATX
Protein Interaction Partner: MAPK9, MAPK8, CDK6, NCOA3, TTF1, CSNK1A1, FOS,
Protein Size: 1068

Poids moléculaire: 115 kDa

ID gène: 4775

NCBI Accession: NM_004555, NP_004546

UniProt: B5B2S0

Pathways: Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Chromatin Binding