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MNAT1 anticorps (N-Term)

MNAT1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poisson zèbre (Danio rerio) WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2792694
  • Antigène Voir toutes MNAT1 Anticorps
    MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
    Épitope
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 33
    • 31
    • 24
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poisson zèbre (Danio rerio)
    Hôte
    • 39
    Lapin
    Clonalité
    • 39
    Polyclonal
    Conjugué
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MNAT1 est non-conjugé
    Application
    • 29
    • 13
    • 13
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Séquence
    DDQGCPRCKT TKYRNPSLKL MVNVCGHTLC ESCVDLLFVR GAGNCPECGT
     Réactivité croisée
    Boeuf (Vache), Chien, Poulet, Mouche des fruits (Drosophila melanogaster), Humain, Souris, Porc, Rat (Rattus)
    Homologie
    Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against MNAT1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human MNAT1
    Top Product
    Discover our top product MNAT1 Anticorps primaire
  • Indications d'application
    WB Suggested Anti-MNAT1 Antibody Titration: 0.2-1 µg/mL
    ELISA Titer: 1:1562500
    Positive Control: 721_B cell lysate.
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 309 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    MNAT1 (Menage A Trois Homolog 1, Cyclin H Assembly Factor (Xenopus Laevis) (MNAT1))
    Autre désignation
    MNAT1 / RNF66 (MNAT1 Produits)
    Sujet
    The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca(2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.Cyclin-dependent kinases (CDKs), which play an essential role in cell cycle control of eukaryotic cells, are phosphorylated and thus activated by the CDK-activating kinase (CAK). CAK is a multisubunit protein that includes CDK7 (MIM 601955), cyclin H (CCNH, MIM 601953), and MAT1. MAT1 (for 'menage a trois-1') is involved in the assembly of the CAK complex.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-498 AA053721.1 1-498 499-1372 BC000820.1 489-1362 1373-1388 BU620200.1 1-16 c
    Alias Symbols: MAT1, RNF66, TFB3, CAP35
    Protein Interaction Partner: RPA3, RPA2, RPA1, CDK7, CDK2, MBP, CTD, CCNH, NGFRAP1, UBC, NKX3-1, USP2, SUPT5H, POLR2A, GTF2H4, GTF2H3, GTF2H1, ERCC2, tat, TRIM39, TRIM34, TRIM17, TRIM2, ICK, TRIM31, RNF41, RNF7, TRIM26, MKRN3, TRIM21, MDM4, BRCA1, TRIML1, RNF32, TRIM9, TRIM5, XBP1P1,
    Protein Size: 309
    Poids moléculaire
    36 kDa
    ID gène
    4331
    NCBI Accession
    NM_002431, NP_002422
    UniProt
    P51948
    Pathways
    Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase
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