PTPN21 anticorps (Center)

N° du produit ABIN2793391

Détail du produit anti-PTPN21 anticorps

Antigène: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Épitope: AA 751-780, Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Rabbit Anti-Human PTPD1 (Center) Antibody

Immunogène: This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of anti-PTPD1 Pab , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur PTPN21

Antigène: PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))

Autre désignation: PTPD1 (PTPN21 Produits)

Synonymes: anticorps PTPD1, anticorps PTPRL10, anticorps Ptp2E, anticorps protein tyrosine phosphatase, non-receptor type 21, anticorps PTPN21, anticorps Ptpn21

Sujet:

Target Description: PTPD1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

Gene Symbol: PTPN21

Poids moléculaire: 133281 Da

ID gène: 11099

UniProt: Q16825