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SGOL2 anticorps (Center)

SGOL2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2795993
  • Antigène Voir toutes SGOL2 Anticorps
    SGOL2 (Shugoshin-Like 2 (SGOL2))
    Épitope
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 391-419, Center
    Reactivité
    • 14
    • 1
    Humain
    Hôte
    • 14
    Lapin
    Clonalité
    • 14
    Polyclonal
    Conjugué
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SGOL2 est non-conjugé
    Application
    • 9
    • 8
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit Anti-Human SGOL2 (Center) Antibody
    Immunogène
    This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SGOL2 Anticorps primaire
  • Indications d'application
    Western Blot
    Recommended Dilutions
    WB: 1:1000SGOL2 Antibody (Center) .
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Stock
    4 °C,-20 °C
    Stockage commentaire
    2-8°C (short-term), -20°C (long-term)
  • Antigène
    SGOL2 (Shugoshin-Like 2 (SGOL2))
    Autre désignation
    SGOL2 (SGOL2 Produits)
    Synonymes
    anticorps SGO2, anticorps TRIPIN, anticorps 1110007N04Rik, anticorps 4932411A20Rik, anticorps 5730576N04Rik, anticorps AU018846, anticorps AV008062, anticorps D1Ertd8e, anticorps Tripin, anticorps shugoshin 2, anticorps shugoshin 2A, anticorps SGO2, anticorps Sgo2a
    Sujet

    Target Description: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

    Gene Symbol: SGOL2

    Poids moléculaire
    144739 Da
    ID gène
    151246
    UniProt
    Q562F6
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