SGOL2 anticorps (Center)
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- Antigène Voir toutes SGOL2 Anticorps
- SGOL2 (Shugoshin-Like 2 (SGOL2))
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Épitope
- AA 391-419, Center
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SGOL2 est non-conjugé
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Application
- Western Blotting (WB)
- Fonction
- Rabbit Anti-Human SGOL2 (Center) Antibody
- Immunogène
- This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SGOL2 Anticorps primaire
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- Indications d'application
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Western Blot
Recommended Dilutions
WB: 1:1000SGOL2 Antibody (Center) . - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- 2-8°C (short-term), -20°C (long-term)
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- Antigène
- SGOL2 (Shugoshin-Like 2 (SGOL2))
- Autre désignation
- SGOL2 (SGOL2 Produits)
- Synonymes
- anticorps SGO2, anticorps TRIPIN, anticorps 1110007N04Rik, anticorps 4932411A20Rik, anticorps 5730576N04Rik, anticorps AU018846, anticorps AV008062, anticorps D1Ertd8e, anticorps Tripin, anticorps shugoshin 2, anticorps shugoshin 2A, anticorps SGO2, anticorps Sgo2a
- Sujet
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Target Description: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
Gene Symbol: SGOL2
- Poids moléculaire
- 144739 Da
- ID gène
- 151246
- UniProt
- Q562F6
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