ATP6V0B anticorps (Center)

N° du produit ABIN2797005

Détail du produit anti-ATP6V0B anticorps

Antigène: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Épitope: AA 104-131, Center

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V0B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: Rabbit Anti-Human ATP6V0B (Center) Antibody

Immunogène: This ATP6V0B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-131 amino acids from the Central region of human ATP6V0B.

Isotype: Ig Fraction

Information d'application

Indications d'application: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50ATP6V0B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Stock: 4 °C,-20 °C

Stockage commentaire: 2-8°C (short-term), -20°C (long-term)

Détails sur ATP6V0B

Antigène: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Autre désignation: ATP6V0B (ATP6V0B Produits)

Synonymes: anticorps ATP6F, anticorps HATPL, anticorps VMA16, anticorps 2310024H13Rik, anticorps Atp6f, anticorps ATPase H+ transporting V0 subunit b, anticorps ATPase, H+ transporting, lysosomal V0 subunit B, anticorps ATPase H+ transporting V0 subunit B, anticorps ATP6V0B, anticorps Atp6v0b

Sujet:

Target Description: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.

Gene Symbol: ATP6V0B

Poids moléculaire: 21406 Da

ID gène: 533

UniProt: Q99437

Pathways: Transition Metal Ion Homeostasis, Proton Transport