Caveolin-1 anticorps

N° du produit ABIN1944910

Détail du produit anti-Caveolin-1 anticorps

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caveolin-1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Isotype: IgG

Information d'application

Indications d'application: IF: 1:100. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-Caveolin-1 (ABIN1944910)

Vainonen, Aboulaich, Turkina, Strålfors, Vener: "N-terminal processing and modifications of caveolin-1 in caveolae from human adipocytes." dans: Biochemical and biophysical research communications, Vol. 320, Issue 2, pp. 480-6, (2004) (PubMed).

Engelman, Zhang, Lisanti: "Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines." dans: FEBS letters, Vol. 448, Issue 2-3, pp. 221-30, (1999) (PubMed).

Hurlstone, Reid, Reeves, Fraser, Strathdee, Rahilly, Parkinson, Black: "Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines." dans: Oncogene, Vol. 18, Issue 10, pp. 1881-90, (1999) (PubMed).

Glenney: "The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles." dans: FEBS letters, Vol. 314, Issue 1, pp. 45-8, (1992) (PubMed).

Détails sur Caveolin-1

Antigène: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Autre désignation: caveolin 1 (CAV1 Produits)

Synonymes: anticorps fc07c04, anticorps wu:fc07c04, anticorps Cav-1, anticorps bscl3, anticorps cav1, anticorps cav1a, anticorps cgl3, anticorps vip21, anticorps cav1b, anticorps caveolin-1, anticorps cav, anticorps mstp085, anticorps Caveolin-1, anticorps CAV1, anticorps cav-1, anticorps Cav, anticorps caveolin 1, anticorps BSCL3, anticorps CGL3, anticorps MSTP085, anticorps PPH3, anticorps VIP21, anticorps caveolin 1, anticorps caveolin 1 L homeolog, anticorps caveolin 1 S homeolog, anticorps caveolin 1, caveolae protein, anticorps caveolin 1, caveolae protein, 22kDa, anticorps Caveolin, anticorps cav1, anticorps cav1.L, anticorps cav1.S, anticorps CAV1, anticorps Cav1, anticorps cav-1

Sujet: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Poids moléculaire: 20472 Da

ID gène: 857

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals