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BFSP2 anticorps (AA 181-280) (Alexa Fluor 594)

BFSP2 Reactivité: Humain WB, IF (cc), IF (p) Hôte: Lapin Polyclonal Alexa Fluor 594
N° du produit ABIN2810317
  • Antigène Voir toutes BFSP2 Anticorps
    BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))
    Épitope
    • 14
    • 4
    • 2
    • 1
    • 1
    AA 181-280
    Reactivité
    • 23
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 22
    • 3
    Lapin
    Clonalité
    • 22
    • 3
    Polyclonal
    Conjugué
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BFSP2 est conjugé à/à la Alexa Fluor 594
    Application
    • 22
    • 12
    • 12
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human BFSP2/Phakinin
    Isotype
    IgG
    Top Product
    Discover our top product BFSP2 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    BFSP2 (Beaded Filament Structural Protein 2, Phakinin (BFSP2))
    Autre désignation
    BFSP2/ Phakinin (BFSP2 Produits)
    Synonymes
    anticorps CP47, anticorps CP49, anticorps CTRCT12, anticorps LIFL-L, anticorps PHAKOSIN, anticorps AI448593, anticorps CP49INS, anticorps BFSP2, anticorps LOC100222605, anticorps Bfsp2, anticorps zgc:103750, anticorps beaded filament structural protein 2, anticorps beaded filament structural protein 2, phakinin, anticorps BFSP2, anticorps Bfsp2, anticorps bfsp2
    Sujet

    Synonyms: 49 kDa cytoskeletal protein, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, phakinin, Bfps2, Cytoskeletal protein, 49 kD, BFSP2, BFSP2_HUMAN, CP47, CP49, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49,Lens intermediate filament-like light, LL-L, Phakinin, PHAKOSIN.

    Background: Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens. IFs are cytoskeletal structures that typically contain a head, rod and tail domain. Unlike most IFs, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens. Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens. Phakinin copolymerizes with Filensin, another IF protein, to form the 10-nm filamentous structures of the beaded filaments. Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles. Mutations in the gene encoding Phakinin can result in lens cataract.

    ID gène
    3921
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